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CyFlow™ CD1a PE

CyFlow™ CD1a PE
Application: Flow cytometry
Laser: Blue, Green, Yellow
Excitation Maximum: 496 nm, 565 nm
Format/Fluorochrome: PE
Field of Interest: Immunophenotyping
Source Species: Mouse
Isotype: IgG2b
Antigen: CD1a
Regulatory Status: RUO
Target Species: Human
Clonality: monoclonal
Clone: SK9
Alternative Name: CD1, HTA1, R4
Emission Maximum: 576 nm
Order number: BR590568
222,01  EUR *

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CD1a, together with CD1b and CD1c, belongs to group 1 of CD1 glycoproteins. These proteins serve... more
Product information "CyFlow™ CD1a PE"
CD1a, together with CD1b and CD1c, belongs to group 1 of CD1 glycoproteins. These proteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. Unlike CD1b, CD1a is excluded from late endosomal compartments and instead traffics independently in the recycling pathway of the early endocytic system, and CD1a antigen presentation is independent upon vesicular acidification.
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