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CyFlow™ AGPS Purified

CyFlow™ AGPS Purified
Application: Flow cytometry, Western blot
Clonality: monoclonal
Target Species: Human
Regulatory Status: RUO
Source Species: Mouse
Format/Fluorochrome: Purified
Isotype: IgG2a
Antigen: AGPS
Clone: AGPS-03
Field of Interest: Others
Order number: CU923196
187,96  EUR *

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AGPS (alkylglycerone phosphate synthase) is an enzyme that catalyzes the second step of ether... more
Product information "CyFlow™ AGPS Purified"
AGPS (alkylglycerone phosphate synthase) is an enzyme that catalyzes the second step of ether lipid biosynthesis in which acyl-dihydroxyacetone phosphate (acyl-DHAP) is converted to alkyl-DHAP by addition of a long chain alcohol and removal of a long-chain acid anion. The protein is localized to the inner side of the peroxisomal membrane and requires FAD as a cofactor. Mutations in AGPS gene have been associated with type 3 of rhizomelic chondrodysplasia punctata (RCDP3), and Zellweger syndrome. Higher expression of AGPS was observed in BCR/ABL positive leukemias and it was also described to be associated with higher risk of relapse.
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