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CyFlow™ CD1a FITC

CyFlow™ CD1a FITC
Application: Flow cytometry
Antigen: CD1a
Alternative Name: CD1, HTA1, R4
Clone: SK9
Clonality: monoclonal
Format/Fluorochrome: FITC
Target Species: Human
Regulatory Status: RUO
Isotype: IgG2b
Laser: Blue
Excitation Maximum: 490 to 495 nm
Emission Maximum: 518 nm
Source Species: Mouse
Field of Interest: Immunophenotyping
Order number: CW604703
187,96  EUR *

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CD1a, together with CD1b and CD1c, belongs to group 1 of CD1 glycoproteins. These proteins serve... more
Product information "CyFlow™ CD1a FITC"
CD1a, together with CD1b and CD1c, belongs to group 1 of CD1 glycoproteins. These proteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. Unlike CD1b, CD1a is excluded from late endosomal compartments and instead traffics independently in the recycling pathway of the early endocytic system, and CD1a antigen presentation is independent upon vesicular acidification.
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